Quinupramine

Quinupramine (Kevopril, Kinupril, Adeprim, Quinuprine) is a tricyclic antidepressant (TCA) used in Europe for the treatment of depression.

Pharmacologically, quinupramine acts in vitro as a strong muscarinic acetylcholine receptor antagonist (anticholinergic) and H₁ receptor antagonist (antihistamine), moderate 5-HT₂ receptor antagonist, and weak serotonin and norepinephrine reuptake inhibitor. It has negligible affinity for the α₁-adrenergic, α₂-adrenergic, β-adrenergic, or D₂ receptor.

单词	Quinupramine
释义	Quinupramine 英语百科 Quinupramine Quinupramine (Kevopril, Kinupril, Adeprim, Quinuprine) is a tricyclic antidepressant (TCA) used in Europe for the treatment of depression. Pharmacologically, quinupramine acts in vitro as a strong muscarinic acetylcholine receptor antagonist (anticholinergic) and H₁ receptor antagonist (antihistamine), moderate 5-HT₂ receptor antagonist, and weak serotonin and norepinephrine reuptake inhibitor. It has negligible affinity for the α₁-adrenergic, α₂-adrenergic, β-adrenergic, or D₂ receptor.
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