Some holoenzymes, such as pyruvate dehydrogenase, are highly compex, with several cofactors.
有一些全酶是高度复杂的，如丙酮酸脱氢酶。
Pyruvate dehydrogenase
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And pyruvate dehydrogenase is the connection between those two.
丙酮酸脱气酶是连系两者的纽带。
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Pyruvate dehydrogenase
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Pyruvate dehydrogenase is the first component enzyme of pyruvate dehydrogenase complex (PDC). The pyruvate dehydrogenase complex contributes to transforming pyruvate into acetyl-CoA by a process called pyruvate decarboxylation (Swanson Conversion). Acetyl-CoA may then be used in the citric acid cycle to carry out cellular respiration, so pyruvate dehydrogenase contributes to linking the glycolysis metabolic pathway to the citric acid cycle and releasing energy via NADH.
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