This paper texted the process to prepare metadoxine from vitamine B6 hydrochloric acid salt ,pyroglutamic acid and isoproanol.
本文以维生素B6氯化氢盐、焦谷氨酸和异丙醇为原料,固相合成美他多辛,纯度达96.3%。
| 单词 | Pyroglutamic acid |
| 释义 |
Pyroglutamic acid
英语例句库
This paper texted the process to prepare metadoxine from vitamine B6 hydrochloric acid salt ,pyroglutamic acid and isoproanol. 本文以维生素B6氯化氢盐、焦谷氨酸和异丙醇为原料,固相合成美他多辛,纯度达96.3%。
英语百科
Pyroglutamic acidPyroglutamic acid (also known as PCA, 5-oxoproline, pidolic acid, or pyroglutamate for its basic form) is an uncommon and little studied amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam. It is a metabolite in the glutathione cycle that is converted to glutamate by 5-oxoprolinase. Pyroglutamate is found in many proteins including bacteriorhodopsin. N-terminal glutamic acid and glutamine residues can spontaneously cyclize to become pyroglutamate. This is one of several forms of blocked N-terminals which present a problem for N-terminal sequencing using Edman chemistry, which requires a free primary amino group not present in pyroglutamic acid. The enzyme pyroglutamate aminopeptidase can restore a free N-terminus by cleaving off the pyroglutamate residue. |
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