Process analytical chemistry

Process Analytical Chemistry (PAC), is similar to Process Analytical Technology (PAT) (for example used for the pharmaceutical industry) has its origins as a specialized form of analytical chemistry used for process manufacturing. Process analytical chemistry is the application of analytical chemistry with specialized techniques, algorithms, and sampling equipment for solving problems related to chemical processes. The chemical processes are for production and quality control of manufactured products, and process analytical technology is used to determine the physical and chemical composition of the desired products during a manufacturing process. It is first mentioned in the chemical literature in 1946(1,2).