In females, primary sex characteristic dysfunction includes amenorrhea or absence of menstruation, or oligomenorrhea or irregular menstrual cycle.

在女性中，第一性征的功能障碍包括闭经，即无月经，或月经减少，即月经周期不规则。

During puberty, waves of estrogen and progesterone regulate primary sex characteristics, like monthly changes to the ovary stroma to promote egg maturation and ovulation, and changes to the uterine wall lining as part of the menstrual cycle.

在青春期，雌激素和孕酮水平的波动会调节第一性征，如每月卵巢基质的变化促进了卵子成熟和排卵，以及作为月经周期一部分的子宫内膜的变化。

Having an extra X chromosome makes the testicular cells generate less testosterone, which is a hormone responsible for primary sex characteristics like development of the sex organs as well as secondary sex characteristics like height and body shape.

多一条X染色体会让睾丸间质细胞的睾酮产量下降；睾酮这种激素不仅负责第一性征的发育，如性器官发育，也负责第二性征发育，如身高和体形。