聚维酮碘（英语：Povidone-iodine），PVP-I,是一种由聚乙烯吡咯烷酮（PVP）和碘（I）元素组成的络合物。按照干燥品计算（干基），包含9.0％至12.0％的可用碘。

聚维酮碘为世界范围内普遍选用的广谱消毒防腐剂。

Povidone-iodine (PVP-I), brand name Wokadine, Pyodine, and Betadine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.

This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. They carried out tests in vitro to demonstrate anti-bacterial activity, and found that the complex was less toxic in mice than tincture of iodine.