There are two proposed mechanisms that could explain how premature ovarian failure develops.

有两种机制可以解释卵巢早衰的发生。

Hormone replacement therapy, like combined oral contraceptives can be useful for individuals with Turner syndrome, polycystic ovarian syndrome or premature ovarian failure.

激素替代疗法，比如复方口服避孕药，对Turner综合征、多囊卵巢综合症或卵巢早衰患者有效。

Now, in premature ovarian failure, the follicles stop responding to gonadotropin stimulation earlier than usual - that being before the age of 40.

而在卵巢早衰患者中，卵泡更早停止对促性腺激素刺激的反应，即在40岁之前。

Some symptoms of premature ovarian failure are directly related to the absence of ovulation and the low levels of estrogen and progesterone.

卵巢早衰的一些症状与无排卵、雌激素孕激素水平低下直接相关。

Eggs are taken from a donor, fertilized, and then implanted into the hormonally prepared uterus of the woman with premature ovarian failure.

从捐赠者体内取出卵子，受精，然后植入卵巢早衰妇女经激素准备的子宫内。

In premature ovarian failure when estrogen levels are low the pituitary gland attempts to restore balance by increasing production of gonadotropins LH and FSH.

在卵巢早衰中，当雌激素水平较低时，垂体试图通过增加促性腺激素LH和FSH的产生来恢复平衡。

Most women have a normal puberty with regular periods before the disorder develops, but then start having troubles when premature ovarian failure occurs.

大多数女性在疾病进展之前都拥有正常的青春期与规律的月经周期；但当卵巢早衰发生时，就开始出现问题。

Diagnosis of premature ovarian failure can be done by detecting low levels of ovarian hormones, mainly estrogen, and increased levels of LH and FSH.

卵巢早衰的诊断可通过检测出低水平的卵巢激素，主要是雌激素以及升高的LH和FSH水平来判定。

Causes of secondary amenorrhea can also cause primary amenorrhea, and they include functional hypothalamic amenorrhea, polycystic ovary syndrome, hyperprolactinemia, premature ovarian failure and Asherman syndrome.

继发性闭经的病因也可以导致原发性闭经，包括功能性下丘脑性闭经、多囊卵巢综合症、高泌乳素血症、卵巢早衰以及Asherman综合征。

All right, as a quick recap, premature ovarian failure occurs before age 40 and is caused by not having enough follicles in the ovaries or having follicles that don't respond to gonadotropins.

好！快速回顾一下：卵巢早衰发生在40岁之前，是由于卵巢中没有足够的卵泡或卵泡对促性腺激素无反应。