泼尼松龙（英语：Prednisolone），又译作康速龙锭（英语：Donison），是一种合成之副肾皮质荷尔蒙制剂。是一种皮质类固醇药物，是泼尼松的一种活性代谢产物，同时亦作为药物使用。它主要对糖皮质激素活跃，矿物类皮质激素活性低，使其适用于广泛的炎症及自体免疫状况，例如：哮喘、葡萄膜炎、坏疽性脓皮病、类风湿关节炎、溃疡性结肠炎、颞动脉炎及克罗恩病、贝尔氏麻痹、多发性硬化症、集群性头痛、血管炎、急性淋巴细胞白血病和自身免疫性肝炎、系统性红斑狼疮、皮肌炎。它也被用于治疗类肉瘤病，但机制不明。

Prednisolone is a synthetic glucocorticoid, a derivative of cortisol, used to treat a variety of inflammatory and autoimmune conditions and some cancers. It is the active metabolite of the drug prednisone and is used especially in patients with liver failure, as these individuals are unable to metabolize prednisone into active prednisolone; it is primarily metabolized via the liver enzyme, 11-β-hydroxydehydrogenase. Adverse effects are not generally seen with short term therapy, but weight gain, impaired immune response, and behavioral disturbances commonly occur with longer durations of treatment.