Clavulanic acid
(重定向自Potassium Clavulanate)


![The intermediates of the biosynthesis of Clavulanic Acid[3]](/uploads/202502/04/Clavualnic_Acid_Biosynthesis2623.png)
![Proposed mechanism of beta-lactam synthetase in the biosynthesis of clavulanic acid.[3]](/uploads/202502/04/Beta-lactam_synthetase_mechanism2623.png)
Clavulanic acid (rINN) /ˌklævjuːˈlænᵻk ˈæsᵻd/ is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic, when combined with penicillin-group antibiotics, it can overcome antibiotic resistance in bacteria that secrete β-lactamase, which otherwise inactivates most penicillins.