莫尔兹比港（英语：Port Moresby；巴布亚皮钦语：Pot Mosbi）位于新几内亚岛东南巴布亚湾沿岸，是巴布亚新几内亚的首都。据2009年的统计，城市人口为307,643。

几个世纪前Motu-Koitabu人早先在这片土地上定居，第一位到此地的西方人是1873年到此的约翰·莫尔兹比船长，取名莫尔兹比港是为了纪念船长的父亲海军上将费尔法克斯·莫尔兹比爵士。

根据《经济学人》杂志信息部关于世界各大城市的调查，莫尔兹比港是世界上最不适合居住的城市之一（位列被调查140个城市的第137位）。

虽然莫尔兹比港被中央省环绕着也是该省的首府，但是作为首都的莫尔兹比港并不属该省管理，而独自形成了国家首都区。

Port Moresby (/ˌpɔərt ˈmɔərzbi/; Tok Pisin: Pot Mosbi), also referred to as Moresby and Pom Town, is the capital and largest city of Papua New Guinea (PNG). It is located on the shores of the Gulf of Papua, on the south-eastern coast of the Papuan Peninsula of the island of New Guinea. The city emerged as a trade centre in the second half of the 19th century. During World War II it was a prime objective for conquest by the Imperial Japanese forces during 1942–43 as a staging point and air base to cut off Australia from Southeast Asia and the Americas.