Many different types have been identified most of which are autosomal dominant.

目前已经鉴定出许多不同的类型，其中大多数是常染色体显性的遗传模式。

Causes It is mostly inherited as " autosomal dominant" pattern so patients have positive family history.

原因多为常染色体显性遗传，患者有阳性家族史。

Mutations in BRCA-1 or BRCA-2 are both autosomal dominant mutations, which can be inherited and cause familial breast cancer.

BRCA-1和BRCA-2的突变都是常染色体显性突变，可被遗传并导致家族性乳腺癌。

There are two types of familial, or congenital, protein C and S deficiency; both are inherited in an autosomal dominant manner.

家族性（先天性）蛋白C和S缺乏症有两种，均为常染色体显性遗传。

Individuals with tuberous sclerosis have a mutation in either the gene TSC1 or TSC2, and these mutations have an autosomal dominant inheritance pattern.

结节性硬化症患者的TSC1或TSC2基因发生了突变，为常染色体显性遗传。

All right, as a quick recap, acute intermittent porphyria is an autosomal dominant disorder caused by a deficiency of the enzyme porphobilinogen deaminase in the heme synthesis pathway.

好，快速回顾一下：急性间歇性卟啉病是常染色体显性疾病，由血红素合成途径中缺乏卟胆原脱氨酶导致。

Now most of these gene mutations are inherited in an autosomal dominant pattern, meaning that one copy of an altered SCA gene is enough to cause the disease.

大多数的突变都以常染色体显性模式遗传，这代表一个SCA基因突变的拷贝足以引起这种疾病。

There are also genetic risk factors like having the BRCA-1 or BRCA-2 mutation, which are both autosomal dominant mutations, which in addition to ovarian cancer, carry with them an increased risk of breast cancer.

还有遗传相关的风险因素，如BRCA-1和BRCA-2突变，它们都是常染色体显性突变；除了卵巢癌之外，携带它们也会增加乳腺癌患病风险。

It's autosomal dominant, which means that even if there's a normal copy of the gene, a single mutated copy of the gene – in other words a heterozygous mutation - is sufficient to cause the disease.

这是一种常染色体显性遗传病，这意味着即使有一个正常基因，只要染色体上有一个突变的基因，即杂合突变，就足以致病。