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单词 Polycomb
释义

Polycomb

中文百科

多梳家族蛋白 Polycomb-group proteins

(重定向自Polycomb)
多梳基因FIE在未受精卵(右)中表达(蓝色);但在正处于发育过程的二倍孢子体(左)中表达终止。
Représentation en 3D du complexe PRC2-AEBP2 chez l'humain.

多梳家族蛋白英语:Polycomb-group proteins)是在果蝇中首次发现的能够重塑染色质从而使基因在表观遗传上沉默的一类蛋白质家族。多梳家族蛋白因其可在黑腹果蝇的胚胎发育过程中通过调整染色质结构沉默同源异形基因而著名。

英语百科

Polycomb-group proteins 多梳家族蛋白

(重定向自Polycomb)
The Polycomb gene FIE is expressed (blue) in unfertilised egg cells of the moss Physcomitrella patens (right) and expression ceases after fertilisation in the developing diploid sporophyte (left). In situ GUS staining of two female sex organs (archegonia) of a transgenic plant expressing a translational fusion of FIE-uidA under control of the native FIE promoter

Polycomb-group proteins are a family of proteins first discovered in fruit flies that can remodel chromatin such that epigenetic silencing of genes takes place. Polycomb-group proteins are well known for silencing Hox genes through modulation of chromatin structure during embryonic development in fruit flies (Drosophila melanogaster).

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更新时间:2025/6/17 14:16:35