结节性多动脉炎（Polyarteritis nodosa, PAN）是一种全身性的坏死血管炎，典型的侵犯对象为中型的小动脉，偶尔会影响到小型的动脉。

病人的症状大多以全身的系统性症状表现。可能影响的器官常见的包括肾脏、皮肤、关节、肌肉、神经和胃肠道，大多发生于成年人。

详细的病因目前不明。

Polyarteritis nodosa, also known as panarteritis nodosa, periarteritis nodosa, Kussmaul disease, Kussmaul-Maier disease or PAN, is a systemic vasculitis of small- or medium-sized muscular arteries, typically involving renal and visceral vessels but sparing the pulmonary circulation. Polyarteritis nodosa may present in infants. In polyarteritis nodosa, small aneurysms are strung like the beads of a rosary, therefore making "rosary sign" an important diagnostic feature of the vasculitis.