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单词 Phenylpropanolamine hydrochloride
释义

Phenylpropanolamine hydrochloride

中文百科

苯丙醇胺 Phenylpropanolamine

(重定向自Phenylpropanolamine hydrochloride)

苯丙醇胺(Phenylpropanolamine,PPA),又称去甲基麻黄素去甲麻黄碱,分子式C9H13NO,CAS编号:14838-15-4。是一种苯乙胺类的药物。目前在美国,年轻妇女必须要有处方签才能购买这种药物,其他地区则没有限制。一种本来很常用的收鼻水药物,可以使阻塞的上呼吸道及气管变得畅通。

在香港,最普通的包装是一粒上白下绿的圆型药饼,收鼻水功效非常快,但服后会使人眼困。而在市面上比较常见而含有PPA的药物有Neozap。

英语百科

Phenylpropanolamine 苯丙醇胺

(重定向自Phenylpropanolamine hydrochloride)
RS-Norephedrin
Ball-and-stick model of the phenylpropanolamine molecule


Metabolic pathways of amphetamine in humans

 
 

4-Hydroxyphenylacetone
Phenylacetone
Benzoic acid
Hippuric acid

Amphetamine 
Norephedrine

4-Hydroxyamphetamine
4-Hydroxynorephedrine

Para-Hydroxylation
Para-Hydroxylation
Para-Hydroxylation

Beta-Hydroxylation
Beta-Hydroxylation

OxidativeDeamination

Oxidation
GlycineConjugation


In humans, norephedrine occurs as a metabolite of amphetamine. The beta-hydroxylation of amphetamine is mediated by dopamine β-hydroxylase.
Space filling model of phenylpropanolamine

Phenylpropanolamine (BAN and INN; PPA, β-hydroxyamphetamine), also known as the stereoisomers (−)-norephedrine and norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine chemical classes which is used as a stimulant, decongestant, and anorectic agent. It is commonly used in prescription and over-the-counter cough and cold preparations. In veterinary medicine, it is used to control urinary incontinence in dogs under trade names Propalin and Proin.

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更新时间:2025/6/17 14:45:25