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单词 Phenyl alanine
释义

Phenyl alanine

中文百科

苯丙氨酸 Phenylalanine

(重定向自Phenyl alanine)
在人类苯丙氨酸最终可代谢成一系列不同的物质。

苯丙氨酸(Phenylalanine,简称Phe或F),是二十种常见胺基酸的一种,化学式为:C6H5CH2CH(NH2)COOH,在室温下为粉末状固体。它是一种必需胺基酸,因为分子一端的苯环具有疏水性,所以苯丙胺酸被分类为非极性分子。L-苯丙胺酸(LPA)为一种电中性胺基酸,"UUU"和"UUC"是合成它的密码子。苯丙氨酸为酪氨酸,单胺类信号传导分子的多巴胺,去甲肾上腺素,和肾上腺素,以及皮肤色素的黑色素的前体。苯丙氨酸是在哺乳动物的乳汁中天然发现。它用于食品和饮料产品的制造,并作为以其著名的止痛和抗抑郁作用的营养补充剂出售。它是一种神经调节剂苯乙胺的直接前体,一种常用的膳食补充剂。 人体无法自行合成苯丙氨酸,必须从饮食中摄取,一般由植物生成苯丙胺酸,如下图:

英语百科

Phenylalanine 苯丙氨酸

(重定向自Phenyl alanine)


Human biosynthesis pathway for trace amines and catecholamines[6][7]

 
 

L-Phenylalanine
L-Tyrosine
L-Dopa
Epinephrine

Phenethylamine
p-Tyramine
Dopamine
Norepinephrine

N-Methylphenethylamine
N-Methyltyramine
p-Octopamine
Synephrine
3-Methoxytyramine

AADC
AADC
AADC

PNMT
PNMT
PNMT
PNMT

AAAH
AAAH
COMT
DBH
DBH


Phenylalanine in humans may ultimately be metabolized into a range of different substances.

Phenylalanine (US: /ˌfɛnəlˈælənn/, UK: /ˌfnlˈælənn/; abbreviated as Phe or F) is an α-amino acid with the formula C6H5CH2CH(NH2)COOH. It can be viewed as a benzyl group substituted for the methyl group of alanine, or a phenyl group in place of a terminal hydrogen of alanine. This essential amino acid is classified as neutral, and nonpolar because of the inert and hydrophobic nature of the benzyl side chain. The L-isomer is used to biochemically form proteins, coded for by DNA. The codons for L-phenylalanine are UUU and UUC. Phenylalanine is a precursor for tyrosine; the monoamine neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline); and the skin pigment melanin.

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更新时间:2025/6/17 15:48:08