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单词 phenethylamine
释义

phenethylamine

英汉-汉英词典
苯乙胺
词组 | 习惯用语
您要查找的是不是:
  • amphetamine n. 安非他明
  • phantasmagoria n. 千变万化的风景;幻灯的一种;幻觉效应
  • phenylalanine n. 苯基丙氨酸
  • triphenylarsine 三苯胂
phenethylamine n. 苯乙胺

网络短语:
trimethylsilyl phenethylamine 三甲基硅烷基苯乙胺
2-Phenethylamine 苯乙胺
hydroxy methylphenyl phenethylamine 苯乙胺
3-methoxy-4-hydroxy phenethylamine hydrochloride 甲氧基
中文百科

苯乙胺

苯乙胺与安非他命的结构通式(见下表)。

苯乙胺(Phenethylamine,PEA),或称β-苯乙胺2-苯乙胺,是一种生物碱与单胺类神经递质。苯乙胺有一个结构异构体,即α-苯乙胺或称1-苯乙胺,α-苯乙胺有两个立体异构体:(R)-(+)-1-苯乙胺与(S)-(-)-1-苯乙胺。在人脑中,2-苯乙胺有神经调节物质、神经递质与示踪胺(Trace amine)的作用。苯乙胺是自然化合物,由胺基酸苯丙氨酸借由酶的脱羧作用的方式生化合成。它也可以在很多食物中找到,如巧克力,特别是在微生物发酵之后。一般都认为来自食物的苯乙胺有足够的用量会产生精神上的作用。然而,它很快就被酵素单胺氧化脢所新陈代谢,防止其有效地集中到达脑部。

英语百科

Phenethylamine 苯乙胺

Ball-and-stick model of phenethylamine


Phenethylamine pharmacodynamics in a TAAR1–dopamine neuron

 
 

via AADC


Both amphetamine and phenethylamine induce neurotransmitter release from VMAT2[19][20][21] and bind to TAAR1.[22][23] When either binds to TAAR1, it reduces neuron firing rate and triggers protein kinase A (PKA) and protein kinase C (PKC) signaling, resulting in DAT phosphorylation.[22][23]  Phosphorylated DAT then either operates in reverse or withdraws into the presynaptic neuron and ceases transport.[22][23]


Human biosynthesis pathway for trace amines and catecholamines[2][28]

 
 

L-Phenylalanine
L-Tyrosine
L-Dopa
Epinephrine

Phenethylamine
p-Tyramine
Dopamine
Norepinephrine

N-Methylphenethylamine
N-Methyltyramine
p-Octopamine
Synephrine
3-Methoxytyramine

AADC
AADC
AADC

PNMT
PNMT
PNMT
PNMT

AAAH
AAAH
COMT
DBH
DBH


In humans, catecholamines and phenethylaminergic trace amines are derived from the amino acid phenylalanine.

Phenethylamine (PEA), also known as β-phenylethylamine (β-PEA) and 2-phenylethylamine is an organic compound and a natural monoamine alkaloid, a trace amine, and also the name of a class of chemicals with many members that are well known for their psychoactive and stimulant effects.

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更新时间:2025/6/21 6:51:56