Percoll层析液是生物化学中一种非常高效的层析方法，该方法由Pertoft研究并制定。结合离心技术，可用于离析细胞、细胞器或病毒等。Percoll层析液的主要成分为经过聚乙烯吡咯烷酮（PVP）处理的直径15-30纳米的二氧化硅胶体颗粒悬浊液（在水中的重量百分比浓度为23% w/w）。 因为Percoll层析液的粘度低于其他替代品，所以更加适合密度梯度类实验。与其他替代品相比，Percoll层析液具有相同的摩尔浓度，并且没有毒性，有助于细胞和其他成分。

Percoll商标由GE医疗注册并持有。

Percoll is a tool for more efficient density separation in biochemistry that was first formulated by Pertoft et al.. It is used for the isolation of cells, organelles, and/or viruses by density centrifugation. Percoll consists of colloidal silica particles of 15-30 nm diameter (23% w/w in water) which have been coated with polyvinylpyrrolidone (PVP). Percoll is well suited for density gradient experiments because it possesses a low viscosity compared to alternatives, a low osmolarity and no toxicity towards cells and their constituents.