Randolph Frederick "Randy" Pausch (October 23, 1960 – July 25, 2008) was an American professor of computer science, human–computer interaction, and design at Carnegie Mellon University (CMU) in Pittsburgh, Pennsylvania.

Pausch learned that he had pancreatic cancer in September 2006, and in August 2007 he was given a terminal diagnosis: "3 to 6 months of good health left". He gave an upbeat lecture titled "The Last Lecture: Really Achieving Your Childhood Dreams" on September 18, 2007, at Carnegie Mellon, which became a popular YouTube video and led to other media appearances. He then co-authored a book called The Last Lecture on the same theme, which became a New York Times best-seller.