Cingulin-like 1

Cingulin-like 1, also known as paracingulin or junction-associated-coiled-coil protein (JACOP), is a protein which is encoded by the CGNL1 gene.

The paracingulin polypeptide comprises a globular N-terminal "head" domain and an α-helical C-terminal domain which is presumed to form a coiled-coil dimer. Paracingulin is a paralog of cingulin that arose probably from gene duplication. The CGNL1 gene is conserved among different vertebrate species and has not been so far identified in invertebrates. The homology search highlights that paracingulin and cingulin have 39% identity in the rod tail sequences. They possess also two highly homologous regions in their N-terminus “head” domain including the ZIM region (ZO-1 interaction motif).

单词	Paracingulin
释义	Paracingulin 英语百科 Cingulin-like 1 Cingulin-like 1, also known as paracingulin or junction-associated-coiled-coil protein (JACOP), is a protein which is encoded by the CGNL1 gene. The paracingulin polypeptide comprises a globular N-terminal "head" domain and an α-helical C-terminal domain which is presumed to form a coiled-coil dimer. Paracingulin is a paralog of cingulin that arose probably from gene duplication. The CGNL1 gene is conserved among different vertebrate species and has not been so far identified in invertebrates. The homology search highlights that paracingulin and cingulin have 39% identity in the rod tail sequences. They possess also two highly homologous regions in their N-terminus “head” domain including the ZIM region (ZO-1 interaction motif).
随便看	center of load的意思 center of location的意思 center of magnus force的意思 Center of Maritime Studies的意思 center of mass的意思 center of mass coordinate的意思 Center of mass coordinates的意思 center of mass coordinate system的意思 center of mass determination的意思 center of mass effect的意思 Center of mass frame的意思 center of mass law的意思 center of mass motion的意思 center of mass system的意思 center of mass theorem的意思 center of mean distance的意思 center of measurement的意思 center of moment的意思 center of moments的意思 Center of momentum coordinate system的意思 Center of motion的意思 center of movement的意思 center of normal curvature的意思 Center of origin的意思 center of origin of crop的意思