In women, an area called the periaqueductal gray (or PAG) is activated, stimulating the flight or fight response while the cortex -- which is associated with pain -- lights up, suggesting that there is a connection between pain and pleasure.

在女性中，一个叫做导水管周围灰质（或 PAG）的区域被激活，刺激飞行或战斗反应， 而与疼痛相关的皮质会亮起， 表明疼痛和快乐之间存在联系。