Oxalate decarboxylase

In enzymology, an oxalate decarboxylase (EC4.1.1.2) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are oxalate and H, whereas its two products are formate and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is oxalate carboxy-lyase (formate-forming). This enzyme is also called oxalate carboxy-lyase. This enzyme participates in glyoxylate and dicarboxylate metabolism.