But overdose fluorine can cause skeletal damage, which lesion fairly complicated.There are only osteosclerosis, ossifying around the bone, but osteomalacia, osteoporosis. 但过量氟会引起骨骼的损伤,其病变较复杂,既有骨硬化、骨周化骨,又有骨软化、骨质疏松。
Food and Drug Administration (FDA) has issued a second approvable letter for bazedoxifene, a selective estrogen receptor modulator, for the prevention of postmenopausal osteoporosis. 苯卓昔芬是一种选择性雌激素受体调节剂,为预防绝经后骨质疏松症药物。
骨质疏松症的表面症状为骨质流失和骨组织破坏,从而导致骨质变得脆弱,大大增加骨折的可能性。根据世界卫生组织的指引,骨质疏松症的定义为当一个人的骨矿密度(Bone Mineral Density)比一个健康女性的骨骼矿质密度低于2.5个标准差。
英语百科
Osteoporosis 骨质疏松症
Osteoporosis is a disease where decreased bone strength increases the risk of a broken bone. It is the most common reason for a broken bone among the elderly. Bones that commonly break include the back bones, the bones of the forearm, and the hip. Until a broken bone occurs there are typically no symptoms. Bones may weaken to such a degree that a break may occur with minor stress or spontaneously. Chronic pain and a decreased ability to carry out normal activities may occur following a broken bone.