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单词 Osteopontin
释义

Osteopontin

原声例句
经济学人 Science and technology

These cells secrete a bunch of milk ingredients, including osteopontin.

这些细胞分泌出一系列乳成分,包括骨桥蛋白。

经济学人 Science and technology

Another American startup called BIOMILQ is pursuing osteopontin, a milk protein involved in gut and immune development, through other means: human cells.

另一家名为 BIOMILQ 的美国初创公司正在通过其他方式(即人体细胞)研究骨桥蛋白,一种参与肠道和免疫发育的牛奶蛋白。

英语百科

Osteopontin

Figure 1. Proteolytic cleavage sites for full length osteopontin (OPN-FL). Thrombin exposes the cleaved epitope SVVYGLR (OPN-R), and then CPB removes the c-terminal arginine from OPN-R. The cleaved epitope has a non-RGD domain, which binds to integrin receptors (α4β1, α9β1, and α9β4). Next to the cleaved epitope, there is a RGD domain that interacts with other integrin receptors (αvβ1,3,5, and α5β1).
Osteopontin seen in a lung tissue sample from a patient with ideopathic pulmonary fibrosis.
Not to be confused with Osteocalcin, Osteonectin or Osteoprotegerin (OPG).

Osteopontin (OPN), also known as bone sialoprotein I (BSP-1 or BNSP), early T-lymphocyte activation (ETA-1), secreted phosphoprotein 1 (SPP1), 2ar and Rickettsia resistance (Ric), is a protein that in humans is encoded by the SPP1 gene (secreted phosphoprotein 1). The murine ortholog is Spp1. Osteopontin is a SIBLING (glycoprotein) that was first identified in 1986 in osteoblasts.

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更新时间:2025/6/20 2:25:41