奥西莫（意大利语：Osimo）是位于意大利中部马尔凯大区安科纳省的一个城市。人口约3万人。丝绸是当地的主要产业。奥西莫是奥西莫条约的签订地。

Osimo (anc. Vetus Auximum) is a town and comune of the Marche, Italy, in the province of Ancona, 15 kilometres (9 mi) south of that town by rail. It is on a hill near the Adriatic Sea.

Silk-spinning and the raising of cocoons are carried on.