Opioid receptors also influence everything from mood to normal bodily functions.

阿片类受体的影响范围很广，从情绪到人体日常功能都包括在内。

So what if you could block those opioid receptors from being activated?

如果能阻止那些阿片受体激活，又会怎样呢？

Naloxone binds to opioid receptors but doesn't activate them.

纳洛酮会与阿片类受体结合，但不会激活受体。

Long story short, you can block opioid receptor activation with something called an opioid antagonist.

简而言之，我们可以通过服用一种名叫“阿片拮抗剂”的药物来阻止阿片受体激活。

It may decrease its number of opioid receptors, or the receptors may become less responsive.

体内的阿片类受体数量可能会减少，或者受体的反应会变弱。

These chemicals lock into opioid receptors throughout your body to help dull the pain and generally calm you down.

这些化学物质会锁定人体内的阿片类物质受体，从而有助于减轻疼痛并使你平静下来。

For example, the feeling of runner's high comes from the natural neurotransmitter endorphin activating your opioid receptors.

例如，跑步者高潮就是来自天然神经递质内啡脑，激活了阿片受体。

Opioid receptors can adapt, often in a short amount of time, to expect opioids.

阿片受体通常可以在短时间内适应预期阿片类药物。

But it also implicates signaling at opioid receptors.

但它也涉及阿片受体的信号。

Each of these drugs has slightly different chemistry, but all act on the body's opioid system by binding to opioid receptors in the brain.

各种阿片类药物的化学性质都略有不同，但都会与大脑中的阿片类受体结合， 从而作用于人体的" 愉悦系统" 。

Opioids work by binding to and activating the opioid receptors located throughout the body, blocking pain signals.

阿片类药物通过结合并激活遍布全身的阿片受体来发挥作用，阻断疼痛信号。

Endorphins bind to what are known as opioid receptors on neurons all over your body, affecting other chemical signaling that your brain interprets as pain.

内啡肽与全身神经元上所谓的阿片受体结合，影响大脑将其解释为疼痛的其他化学信号。

When a drug binds to opioid receptors, it triggers the release of dopamine, which is linked to feelings of pleasure and may be responsible for the sense of euphoria that characterizes an opioid high.

药物与阿片类受体的结合会触发多巴胺的分泌。多巴胺与愉悦感有关，摄取阿片类药物时标志性的愉悦感可能就是由它引起的。

When we don't have enough signaling at opioid receptors, we can feel alone in a room full of people we care about and love, who love us.

当我们在阿片受体上没有足够的信号时，我们会在一个满是我们关心和爱的人的房间里感到孤独， 他们爱我们。

It works by targeting opioid receptors in the body that do not seem to have the reinforcing effects in the brain's reward circuitry that are the usual causes of addiction.

它的工作原理是针对体内的阿片受体，这些受体似乎在大脑的奖赏回路中没有增强作用，而这是导致成瘾的常见原因。