His actions operated against the principles of freedom.

他的行为与自由的原则相违背。

The secret service operated against the enemy during the war.

在战争期间对敌方展开地下工作。

The new law operates against us.

这一新法令对我们不利。

The Zeitgeist of these centuries operated against the development of a pure science.

这几世纪的时代精神阻碍了纯粹科学的发展。