Oil of clove, also known as clove oil, is an essential oil extracted from the clove plant, Syzygium aromaticum. It has the CAS number 8000-34-8.

Clove oil is a natural analgesic and antiseptic, used primarily in dentistry for its main ingredient eugenol. It can also be purchased in pharmacies over the counter as a home remedy for dental pain relief, mainly toothache. It is also often found in the aromatherapy section of health food stores, and is used in the flavoring of some medicines. Madagascar and Indonesia are the main producers of clove oil.