The award cited their discoveries on nucleoside base modifications which had fundamentally changed the understanding of how mRNA interacted with the immune system.
诺奖委员会表示,他们发现了核苷碱基修饰,从根本上改变了人们对信使核糖核酸如何与免疫系统相互作用的理解。
单词 | nucleoside | ||||||||||||||||||
释义 |
nucleoside
|
核碱基 | 核苷 | 去氧核苷 |
---|---|---|
![]() 腺嘌呤 | ![]() 腺苷 A |
![]() 去氧腺苷 dA |
![]() 鸟嘌呤 | ![]() 鸟苷 G |
![]() 去氧鸟苷 dG |
![]() 胸腺嘧啶 | ![]() 胸苷 T |
![]() 去氧胸苷 dT |
![]() 尿嘧啶 | ![]() 尿苷 U |
![]() 去氧尿苷 dU |
![]() 胞嘧啶 | ![]() 胞苷 C |
![]() 去氧胞苷 dC |
核苷酸的结构:
Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group. A nucleoside consists simply of a nucleobase (also termed a nitrogenous base) and a 5-carbon sugar (either ribose or deoxyribose), whereas a nucleotide is composed of a nucleobase, a five-carbon sugar, and one or more phosphate groups. In a nucleoside, the base is bound to either ribose or deoxyribose via a beta-glycosidic linkage. Examples of nucleosides include cytidine, uridine, adenosine, guanosine, thymidine and inosine.
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