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单词 Nivolumab
释义

Nivolumab

原声例句
经济学人-科技

Nivolumab and lambrolizumab gum up another surface protein, PD-1; and a fourth, so new that it still goes by its laboratory identifier of MPDL3280A, binds to PD-L1, a protein that would otherwise help PD-1 to do its job.

Nivolumab和lambrolizumab扰乱另一种表面蛋白PD-1。第四种蛋白最近才发现,还使用着实验室标识符MPDL3280A,它可以绑定到PD-L1上,而PD-L1会反过来协助PD-1蛋白完成任务。

英语百科

Nivolumab

Nivolumab (nye vol' ue mab), marketed as Opdivo, is a humanized IgG4 anti-PD-1 monoclonal antibody used to treat cancer. Nivolumab works as a checkpoint inhibitor, blocking a signal that would have prevented activated T cells from attacking the cancer, the allowing the immune system to clear the cancer. It was discovered at Medarex, developed by Medarex and Ono Pharmaceutical, and brought to market by Bristol-Myers Squibb (which acquired Medarex in 2009) and Ono.

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更新时间:2025/6/22 22:54:54