Neuromuscular-blocking drug

Global view of a neuromuscular junction:1. Axon2. Motor end-plate3. Muscle fiber4. Myofibril

Detailed view of a neuromuscular junction:1. Presynaptic terminal2. Sarcolemma3. Synaptic vesicle4. Nicotinic acetylcholine receptor5. Mitochondrion

Mind Map showing a summary of Neuromuscular nondepolarizing agent

Mind Map showing a summary of Neuromuscular depolarizing agent

Neuromuscular-blocking drugs block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. This is accomplished either by acting presynaptically via the inhibition of acetylcholine (ACh) synthesis or release or by acting postsynaptically at the acetylcholine receptors of the motor nerve end-plate. While some drugs act presynaptically (such as botulinum toxin and tetanus toxin), those of current clinical importance work postsynaptically.

单词	Neuromuscular blockade
释义	Neuromuscular blockade 英语百科 Neuromuscular-blocking drug Neuromuscular-blocking drugs block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. This is accomplished either by acting presynaptically via the inhibition of acetylcholine (ACh) synthesis or release or by acting postsynaptically at the acetylcholine receptors of the motor nerve end-plate. While some drugs act presynaptically (such as botulinum toxin and tetanus toxin), those of current clinical importance work postsynaptically.
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Neuromuscular blockade

Neuromuscular-blocking drug