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单词 Neuromodulin
释义

Neuromodulin

英语百科

Gap-43 protein

(重定向自Neuromodulin)

Growth Associated Protein 43 also known as GAP43 is a protein that in humans is encoded by the GAP43 gene.

GAP43 has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development, during axonal regeneration and is phosphorylated after long-term potentiation (LTP) and after learning (reference needed). This protein is considered a crucial component of the axon and presynaptic terminal, its null mutation leading to death within days after birth due to axon pathfinding defects.

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更新时间:2025/6/18 16:37:24