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单词 Neuromelanin
释义

Neuromelanin

英语百科

Neuromelanin

5,6-dihydroxyindole, the monomer out of which neuromelanin polymers are formed.
Photomicrograph of a region of substantia nigra in a Parkinson's patient showing Lewy bodies and Lewy neuritis: The 20 × magnification image shows strand-like Lewy neurites and rounded Lewy bodies of various sizes. Neuromelanin-laden cells of the substantia nigra are visible in the background.

Neuromelanin (NM) is a dark pigment found in the brain which is structurally related to melanin. It is a polymer of 5,6-dihydroxyindole monomers. Neuromelanin is expressed in large quantities in catecholaminergic cells of the substantia nigra pars compacta and locus coeruleus, giving dark color to the structures.

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更新时间:2025/6/21 0:34:20