Someone who makes big negative changes is a destroyer.

而做出巨大消极改变的人是破坏者。

Not only they have failed in bringing about positive change, they actually brought about negative change.

不仅没有实现正面的改变 实际上是带去了负面的改变。

On the other hand, negative changes often need to be corrected for.

另一方面，消极的变化往往需要被纠正。

Just as power is used to make negative changes, it is also used to make positive changes.

正如权力被用来做出消极的改变一样，它也能被用来做出积极的改变。

For example, someone with power can make positive changes or negative changes; they can make big changes or small changes.

例如，有权力的人可以做出积极或消极的改变；他们可以做出大的改变，也可以做出小的改变。

Someone who makes small positive changes is a hero, and someone who makes small negative changes is a criminal.

做出微小的积极改变的人是英雄，做出微小的消极改变的人是罪犯。

If someone has a negative change in mood, the pleaser may have an internal struggle with feeling anxious, upset, or stressed.

如果某人的情绪发生了消极的变化，讨好型人格的人可能会感到焦虑、不安或有压力。

Alzheimer's disease starts with negative changes in the brain years, if not decades, prior to clinical symptoms.

阿尔茨海默病始于大脑在出现临床症状之前数年甚至数十年的负面变化。

And some people would say it's a negative change, or you know: " going mad" .

有些人会说这是一个负面变化， 或者你知道：“发疯” 。

Long story short, this event would have huge rippling effects throughout essentially every part of the planet, most of which would be negative changes.

简单来说，这一事件将对地球上的每一个地方都产生巨大的涟漪效应，其中大部分将是负面的变化。

Many social scientists worry about test scores resulting in sweeping and often negative changes for test takers, sometimes with long-term life consequences.

许多社会科学家担心考试成绩会给应试者带来全面且通常是负面的变化，有时会带来长期的生活后果。

Studies of internet addiction consistently show that it is this constant novelty at a click that can cause addiction and the negative brain changes associated with addiction.

对网络成瘾的研究不断显示出，这种一个点击所带来的不断的新奇感导致的成瘾，而且大脑的不乐观消极性改变与成瘾有关联。

We have other changes that happen, we have: " old" , " tired" , " ill" , these are also things people see as negative changes, but we don't use " go" with these things.

我们还有其他变化发生， 我们有：“老” 、“累” 、“病”，这些也是人们认为是负面变化的东西， 但我们不会用“走” 来形容这些东西。

And finally we have the fourth major symptom cluster: pervasive negative changes in emotions and belief, like feelings in excessive guilt, fear, or shame -- or no longer getting enjoyment out of what you used to.

最后，我们有第四个主要症状群：情绪和信念的普遍负面变化，比如过度内疚、恐惧或羞愧的感觉——或者不再从你过去的事情中得到乐趣。

After all, if we're planning on eventually sending a lot of people to Mars and back, we'll need to know how the trip will affect them and how to prevent these negative changes, and make future space travel a lot safer.

毕竟， 如果我们计划最终将大量人员送往火星并返回，我们需要知道这次旅行将如何影响他们以及如何防止这些负面变化，并使未来的太空旅行更加安全。