One problem with this study trying to manage heavy drinking with Naltrexone is that the patients were encouraged to be abstinent while on the naltrexone.

这项研究试图通过纳曲酮来控制酗酒，但问题是，患者在摄入纳曲酮的同时一点儿酒都不能沾。

Here is a graph from Dr. David Sinclair in the Roy Eskapa book showing that in rats, after only 5 " extinction sessions, " that is a naltrexone plus alcohol session, the rats were already drinking 10 times less than they normally did.

Roy Eskapa 在其书中引用了 David Sinclair 博士制作的一幅直方图，该图显示，仅用了 5 个“药理灭绝”（纳曲酮+酒精）疗程，有酒瘾的那些老鼠饮酒量便降到了过去的十分之一。