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单词 Multivesicular body
释义

Multivesicular body

中文百科

核内体 Endosome

(重定向自Multivesicular body)

电子显微放大照片中人类海拉细胞中的核内体。E:初级内体,M:次级内体,L:溶酶体。标注比例尺:500纳米

核内体英语:Endosome,又称内体)在细胞生物学中指的是一种真核细胞中的膜结合细胞器,属于一种囊泡结构。作为细胞内吞作用中运载途径的一个区室,核内体从细胞质膜被传递到溶酶体被其降解,或者再循环回到细胞质膜。一个成熟的内体直径大约500纳米。

英语百科

Endosome 核内体

(重定向自Multivesicular body)
Electron micrograph of endosomes in human HeLa cells. Early endosomes (E - labeled for EGFR, 5 minutes after internalisation, and transferrin), late endosomes/MVBs (M) and lysosomes (L) are visible. Bar, 500 nm.
Diagram of the pathways that intersect endosomes in the endocytic pathway of animal cells. Examples of molecules that follow some of the pathways are shown, including receptors for EGF, transferrin, and lysosomal hydrolases. Recycling endosomes, and compartments and pathways found in more specialized cells, are not shown.

In cell biology, an endosome is a membrane-bound compartment inside eukaryotic cells. It is a compartment of the endocytic membrane transport pathway originating from the trans Golgi membrane. Molecules or ligands internalized from the plasma membrane can follow this pathway all the way to lysosomes for degradation, or they can be recycled back to the plasma membrane. Molecules are also transported to endosomes from the trans-Golgi network and either continue to lysosomes or recycle back to the Golgi. Endosomes can be classified as early, sorting, or late depending on their stage post internalization. Endosomes represent a major sorting compartment of the endomembrane system in cells. In HeLa cells, endosomes are approximately 500 nm in diameter when fully mature.

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更新时间:2025/6/19 18:11:20