Causes of secondary amenorrhea can also cause primary amenorrhea, and they include functional hypothalamic amenorrhea, polycystic ovary syndrome, hyperprolactinemia, premature ovarian failure and Asherman syndrome.

继发性闭经的病因也可以导致原发性闭经，包括功能性下丘脑性闭经、多囊卵巢综合症、高泌乳素血症、卵巢早衰以及Asherman综合征。

Finally, a structural cause of secondary amenorrhea is intrauterine adhesions, or Asherman syndrome, which is when there is scar tissue inside the uterine cavity, typically in a female that has undergone uterine instrumentation in the past.

最后，继发性闭经的一种解剖结构性病因是宫腔粘连，即Asherman综合征，也就是宫腔内存在疤痕组织，典型的原因是女性曾经有过子宫有创检查。