A condition where you might have multiple follicular cysts is polycystic ovary syndrome, which is caused by a dysfunction in the hypothalamic-pituitary-ovarian axis that causes chronic anovulation, which may lead to amenorrhea, or absent menstruation, and excess androgen production.

患多囊卵巢综合征（PCOS）时，可能会有多个滤泡囊肿产生，由下丘脑-垂体-卵巢轴功能失调导致；这也会造成长期无排卵，进而可能引起闭经，即月经次数减少，和雄激素生成过量。