非洲猪瘟病毒科（Asfarviridae）是双链DNA病毒中的一科，该类病毒主要感染脊椎动物，下有一属：

猪瘟：脾脏有梗塞，但非洲猪瘟感染猪脾脏可肿大一倍以上。 猪丹毒：脾脏也会肿大，但浆膜层出血为块状，而非点状。 沙门氏杆菌症：肝脏有粟粒状白色坏死病灶。

Asfarviridae is a family of viruses that primarily infects swine, resulting in an onset of African swine fever. There is a single genus in this family: Asfivirus. The name of this family and genus are derived from the acronym: African swine fever and related viruses. Only a single species has been described to date for this genus.