莫索罗（葡萄牙语：Mossoró）是巴西北大河州的一个市镇。总面积2110.207平方公里，总人口229787人，人口密度108.9人/平方公里。莫索罗为北大河州第二大城市。

莫索罗全年炎热，是巴西全国最热的城市之一。

Mossoró (Portuguese pronunciation: [mosoˈɾɔ]) is the second most populous city in the state of Rio Grande do Norte, Brazil, and also the largest municipality of that state. It is equidistant (four hours' drive) from Natal (approximately 277 km or 172 miles), the state capital of Rio Grande do Norte, and from Fortaleza (approximately 260 km or 161.5 miles), the capital of the state of Ceará. It is located nearly in the center of the Nordeste region, which has about 53.6 million people (28% of Brazil's population). It is also in the heart of Brazil's salt production area. Situated in the Agreste-Potiguar mesoregion, Mossoró is the country's largest land-based petroleum producer.