Molina de Segura is a municipality of Spain in the autonomous community and province of Murcia. It is located 10 km from the provincial capital, Murcia.

The town has a line of walls dating to the Almohad era (11th-13th centuries).

The town of Molina de Segura is located in Europe, in the east of the Iberian Peninsula, belonging to the kingdom of Spain, and part of the Region of Murcia. The township has an area of 169 km with flora and fauna belonging to the very dry Mediterranean climate (340 mm of rainfall per year) to which it belongs. It borders the towns of Las Torres de Cotillas, Alguazas, Lorquí, Ulea, Archena, Abarán, Blanca, Murcia and Fortuna. It has the fourth largest population in the region after Murcia, Cartagena and Lorca, with over 60,000 inhabitants. It is located 10 km north of the capital. Through it passes the N-301 highway that runs from Madrid to Cartagena. From Murcia Molina de Segura can be reached by two motorways, one direct and one urban population that surrounds and connects the Mediterranean motorway. It has a train to Madrid, from next Alguazas. The airports of Alicante and San Javier and the seaport of Cartagena are located half an hour away by car.