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单词 5S ribosomal RNA
释义

5S ribosomal RNA

中文百科

5S 核糖体RNA

5S rRNA的三维图像。这是大肠杆菌核糖体亚基 5S rRNA 的结构,根基于低温电子显微重建。[1]
5S rRNA分子的三维图像。[2]
Figure 2: Atomic 3D structure of the 50S subunit from Haloarcula marismortui, PDB 1FFK. Proteins are shown in blue, 23S rRNA in orange and 5S rRNA in yellow.[11] 5S rRNA together with the ribosomal proteins L5 and L18 and the domain V of 23S rRNA constitute the bulk of the central protuberance (CP).

5S 核糖体RNA5S rRNA)是原核生物及真核生物细胞的核糖体大亚基**有的一种双链RNA。

  • 该rRNA是在原核生物核糖体50S亚基的一部分。
  • 该rRNA在真核生物中由RNA聚合酶III合成(其他真核细胞中的rRNA都由45S RNA前体(由RNA聚合酶I合成)裂解而成)。在爪蟾(Xenopus) 的卵母细胞中,人们发现转录因子TFIIIA的9-锌指结构中的第4至第7指能与5S rRNA的核心区域结合。
英语百科

5S ribosomal RNA 5S 核糖体RNA

Figure 1: A 3D representation of a 5S rRNA molecule. This structure is of the 5S rRNA from the Escherichia coli 50S ribosomal subunit and is based on a cryo-electron microscopic reconstruction.[2]
Figure 2: Atomic 3D structure of the 50S subunit from Haloarcula marismortui, PDB 1FFK. Proteins are shown in blue, 23S rRNA in orange and 5S rRNA in yellow.[11] 5S rRNA together with the ribosomal proteins L5 and L18 and the domain V of 23S rRNA constitute the bulk of the central protuberance (CP).
Figure 3: Consensus secondary structure models of 5S rRNA based on the covariance models used to search for 5S rRNA genes. Models for: A) bacteria, archaea, and eukaryotic nuclei, B) plastids, and C) mitochondria. The IUPAC code letters and circles indicate conserved nucleotides and positions with variable nucleotide identity, respectively. Conserved and covariant substitutions in canonical (Watson-Crick) base-pairs are shaded.

The 5S ribosomal RNA (5S rRNA) is an approximately 120 nucleotide-long ribosomal RNA molecule with a mass of 40 kDa. It is a structural and functional component of the large subunit of the ribosome in all domains of life (bacteria, archaea, and eukaryotes), with the exception of mitochondrial ribosomes of fungi and animals. The designation 5S refers to the molecule’s sedimentation velocity in an ultracentrifuge, which is measured in Svedberg units (S).

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更新时间:2025/6/22 3:33:48