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单词 Midostaurin
释义

Midostaurin

英语百科

Midostaurin

Ball-and-stick model of the midostaurin molecule

Midostaurin (PKC412) is a multi-target protein kinase inhibitor being investigated for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). It is a semi-synthetic derivative of staurosporine, an alkaloid from the bacterium Streptomyces staurosporeus, and is active in patients with mutations of CD135 (FMS-like tyrosine kinase 3 receptor, FLT3).

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更新时间:2025/6/23 2:37:54