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单词 Mevalonate
释义

Mevalonate

中文百科

甲羟戊酸 Mevalonic acid

(重定向自Mevalonate)
甲羟戊酸途径。

甲羟戊酸, 甲瓦龙酸(Mevalonic acid, MVA)是生物化学中甲羟戊酸途径的前体化合物,是胆固醇和众多类萜生物合成的中间体之一。呈油状,易溶于水和极性有机溶剂。溶液中容易内酯化,与六元的甲羟戊酸内酯(末端羟基与羧基缩合)形成平衡。

3位碳有手性,但只有3R异构体能为生物体所利用。

羊毛甾醇 · 7-烯胆甾烷醇 · 7-脱氢胆固醇 · 胆固醇

医学导航:遗传代谢缺陷

代谢、k,c/g/r/p/y/i,f/h/s/l/o/e,a/u,n,m

k,cgrp/y/i,f/h/s/l/o/e,au,n,m,人名体征

英语百科

Mevalonic acid 甲羟戊酸

(重定向自Mevalonate)
Mevalonate pathway

Mevalonic acid (MVA) is a key organic compound in biochemistry. The name is a contraction of dihydroxymethylvalerolactone. The carboxylate anion of mevalonic acid, which is the predominant form in biological environments is known as mevalonate, and is of major pharmaceutical importance. Drugs such as the statins (which lower levels of cholesterol) stop the production of mevalonate by inhibiting HMG-CoA reductase.

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更新时间:2025/6/18 20:21:21