In enzymology, a mevaldate reductase (EC1.1.1.32) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are (R)-mevalonate and NAD, whereas its 3 products are mevaldate, NADH, and H.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is (R)-mevalonate:NAD oxidoreductase. This enzyme is also called mevalonic dehydrogenase.