Methylnitronitrosoguanidine

Methylnitronitrosoguanidine (MNNG or MNG) is a biochemical tool used experimentally as a carcinogen and mutagen. It acts by adding alkyl groups to the O of guanine and O of thymine, which can lead to transition mutations between GC and AT. These changes do not cause a heavy distortion in the double helix of DNA and thus are hard to detect by the DNA mismatch repair system.

单词	Methylnitronitrosoguanidine
释义	Methylnitronitrosoguanidine 英语百科 Methylnitronitrosoguanidine Methylnitronitrosoguanidine (MNNG or MNG) is a biochemical tool used experimentally as a carcinogen and mutagen. It acts by adding alkyl groups to the O of guanine and O of thymine, which can lead to transition mutations between GC and AT. These changes do not cause a heavy distortion in the double helix of DNA and thus are hard to detect by the DNA mismatch repair system.
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