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单词 Methylglyoxal synthase
释义

Methylglyoxal synthase

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Methylglyoxal synthase

Crystal structure (PDB ID: 1EGH) of methylglyoxal synthase homohexamer with residues of one active site highlighted. Three active sites exists within the three major grooves. Image generated with PyMOL.
Active site residues of methylglyoxal synthase (Lys23, Thr45, Thr48, Gly66, His19, His98, Asp71). Image generated from crystal structure (PDB ID: 1EGH) with PyMOL.
Methylglyoxal synthase arrow-pushing mechanism. Recreated on ChemDraw and adapted from Saadat, D; Harrison, D. H. (1999).

In enzymology, a methylglyoxal synthase (EC4.2.3.3) is a enzyme that catalyzes the chemical reaction

Hence, this enzyme has one substrate, DHAP, and two products, methylglyoxal and phosphate. Attempts to observe reversibility of this reaction have been unsuccessful.

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更新时间:2025/6/21 14:50:44