Mesembrine

Mesembrine is an alkaloid present in Sceletium tortuosum (kanna). It has been shown to act as a serotonin reuptake inhibitor (K_i = 1.4 nM), and more recently, has also been found to behave as a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4) (K_i = 7,800 nM). As such, mesembrine may contribute to the antidepressant effects of kanna. The levorotary isomer, (−)-mesembrine, is the natural form.

单词	Mesembrine
释义	Mesembrine 英语百科 Mesembrine Mesembrine is an alkaloid present in Sceletium tortuosum (kanna). It has been shown to act as a serotonin reuptake inhibitor (K_i = 1.4 nM), and more recently, has also been found to behave as a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4) (K_i = 7,800 nM). As such, mesembrine may contribute to the antidepressant effects of kanna. The levorotary isomer, (−)-mesembrine, is the natural form.
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