Excitatory postsynaptic potential

（重定向自MEPSP）

This single EPSP does not sufficiently depolarize the membrane to generate an action potential.

The summation of these three EPSPs generates an action potential.

In neuroscience, an excitatory postsynaptic potential (EPSP) is a postsynaptic potential that makes the post synaptic neuron more likely to fire an action potential. This temporary depolarization of postsynaptic membrane potential, caused by the flow of positively charged ions into the postsynaptic cell, is a result of opening ligand-gated ion channels. These are the opposite of inhibitory postsynaptic potentials (IPSPs), which usually result from the flow of negative ions into the cell or positive ions out of the cell. EPSPs can also result from a decrease in outgoing positive charges, while IPSPs are sometimes caused by an increase in positive charge outflow. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC).

单词	MEPSP
释义	MEPSP 英语百科 Excitatory postsynaptic potential （重定向自MEPSP） In neuroscience, an excitatory postsynaptic potential (EPSP) is a postsynaptic potential that makes the post synaptic neuron more likely to fire an action potential. This temporary depolarization of postsynaptic membrane potential, caused by the flow of positively charged ions into the postsynaptic cell, is a result of opening ligand-gated ion channels. These are the opposite of inhibitory postsynaptic potentials (IPSPs), which usually result from the flow of negative ions into the cell or positive ions out of the cell. EPSPs can also result from a decrease in outgoing positive charges, while IPSPs are sometimes caused by an increase in positive charge outflow. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC).
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