脑膜炎双球菌疫苗（Meningoccal vaccine）指的是专门预防脑膜炎双球菌感染的疫苗。不同的疫苗可能对部分或以下几种脑膜炎血清型有效；分别是A、C、W135、和Y等四种 。疫苗至少可以在两年内提供大约85%-100%的防疫效果。只要广泛让民众接种疫苗，它们确实可以降低脑膜炎和败血症的发病机率。疫苗可以借由肌肉注射或是皮下注射的方式给药。

世界卫生组织针对发病率中等或更高甚至是常态性爆发的国家提出建议，应定期施打疫苗。而对于低发病率的国家，则建议让高风险族群保持免疫状态。目前在非洲脑膜炎带的努力目标是希望让一到三十岁的人们可以获得免疫，所以目前脑膜炎A型混合疫苗施打一直在进行。在加拿大和美国，世界卫生组织建议应让青少年以及高风险族群定期施打可对抗四种不同亚型脑膜炎双球菌的疫苗该组织也同样希望要前往麦加朝圣的旅客可以施打疫苗。

Meningococcal vaccine refers to any of the vaccines used to prevent infection by Neisseria meningitidis. Different versions are effective against some or all of the following types of meningococcus: A, C, W135, and Y. The vaccines are between 85 and 100% effective for at least two years. They result in a decrease in meningitis and sepsis among populations where they are widely used. They are given either by injection into a muscle or just under the skin.