《神盾局特工》（英语：Agents of S.H.I.E.L.D.）是一部美国广播公司于2013年制作并播出的电视剧，由乔斯·温登根据漫威漫画中的同名组织神盾局为蓝本创作，属于漫威电影宇宙的系列作品之一，从电影系列的第二阶段开始。「神盾局」（S.H.I.E.L.D.）是「国土战略防御攻击与后勤保障局」（Strategic Homeland Intervention，Enforcement and Logistics Division）的简称，前身为「战略科学军团」（Strategic Scientific Reserve, S.S.R.），在第二次世界大战期间，为了对抗「九头蛇」（HYDRA）而由同盟国联合组成。

Marvel's Agents of S.H.I.E.L.D., or simply Agents of S.H.I.E.L.D., is an American television series created for ABC by Joss Whedon, Jed Whedon, and Maurissa Tancharoen, based on the Marvel Comics organization S.H.I.E.L.D. (Strategic Homeland Intervention, Enforcement, and Logistics Division), a fictional peacekeeping and spy agency in a world of superheroes. It is set in the Marvel Cinematic Universe (MCU), sharing continuity with the films and other television series of the franchise. The series is produced by ABC Studios, Marvel Television, and Mutant Enemy Productions, with Jed Whedon, Tancharoen, and Jeffrey Bell serving as showrunners.